The fastest way to burn a domain is to blast a list you never qualified. Spam complaints spike, deliverability tanks, and your good prospects never see you.
Qualify at the row level
Before anything enters a sequence, I run each row through an LLM prompt that checks the things a filter can't: does this company actually offer a free trial, do they run outbound themselves, does their site match the ICP thesis.
Signals beat titles
Job titles lie. Signals don't. Burner domains forwarding to a main domain mean a team runs cold email. Heavy support headcount plus high web traffic means they need help handling volume. AI turns those messy signals into a clean score you can sort and segment on.
You end up sending less, to better-fit people, with a message built on why they were selected in the first place.